Robert’s CV

Programming & Scripting

Python, R, Java, Unix shell, HTML, CSS, SQL (MySQL, PostgreSQL), GUIs, JavaScript, cloud (GCP, AWS), dashboards, React, MATLAB, Perl

Analysis

machine learning, bioinformatics, software development, large language models, whole genome sequencing, single-cell sequencing, spatial transcriptomics, multi-omics, bulk RNA-sequencing, microbiomics, data annotation & quality control, statistics, biostatistics, electronic health records, fractal & multifractal analysis

Communication

11 peer-reviewed scientific publications, conference abstracts, FDA application, collaboration development, technical proofreading, English language editing

Forta Health (San Francisco, California)
Senior Data Scientist
May 2023–present

• Responsibilities
  • Design and implement statistical experiments to test & validate hypotheses on clinical datasets
  • Carry out advanced data analyses to understand complex datasets and complex problems
  • Lead development of clinical machine learning algorithms which guide the diagnosis and therapy of autism spectrum disorder (ASD) and other medical conditions
  • Communicate design and impact of data science projects and present analytical conclusions in reports to internal and external stakeholders
  • Promote the adoption and integration of new techniques in machine learning and deep learning and put them into practice to develop novel approaches in the healthcare domain
  • Develop dashboards with custom views, components, and database interaction for use across all teams (operations, clinical decision-making, client training, billing, etc.)
  • Collaborate on writing of scientific publications, regulatory documents, and NIH grants
  • Collaborate to drive cross-product efforts to deploy models in care practices
  • Collaborate to drive cross-product efforts to deploy models in care practices
  • Mentor data science interns

Center for Immunology & Inflammation, Feinstein Institutes for Medical Research, Northwell Health (Manhasset, NY)
Consulting Bioinformatician
April 2023–present

• Responsibilities
  • Use single-cell sequencing (RNA, etc.) alongside machine learning techniques to investigate expression and other properties of mixed cell populations
  • Areas of study include the molecular mechanisms of sepsis etiology and development

Center for Genomics & Human Genetics, Feinstein Institutes for Medical Research, Northwell Health (Manhasset, NY)
Data Scientist
June 2021–May 2023

• Mentors: Peter K. Gregersen, MD, Andrew Shih, PhD, and Christine Metz, PhD
• Responsibilities
  • Used human single-cell sequencing (RNA, ATAC, etc.) and spatial transcriptomics, alongside machine learning approaches, to investigate the expression patterns and chromatin accessibility in mixed cell populations
  • Used human whole genome sequencing and other genetics data to identify risk variants and polygenic risk
  • Used cytokine and microbiome data to predict chronic wound healing outcomes
  • Mentored and developed projects for high school, undergraduate, and graduate interns
  • Co-leader of bioinformatics workshops for postdoctoral trainees and faculty
  • Co-instructor for introductory genetics course for PhD and MD-PhD students
  • Phenotypes investigated: endometriosis, renal cell carcinoma, autoimmune disorders, pitch perception, lupus, wounds

Litwin-Zucker Center for the Study of Alzheimer’s Disease and Memory Disorders, Feinstein Institutes for Medical Research, Northwell Health (Manhasset, NY)
Research/Clinical Data Analyst
June 2018–June 2021

• Mentors: Yun Freudenberg-Hua, MD, and Peter Davies, PhD
• Responsibilities
  • Used human whole genome sequences to identify mutation burden and risk variants
  • Created new software and database-interfacing tools
  • Enrolled patients in precision medicine projects, which included conducting cognitive tests
  • Mentored and developed projects for high school and undergraduate summer interns
  • Ran data queries and analyses of health record data for COVID-19 investigations
• Collaborations
  • “Genetic Association and Functional Mapping Analysis of Alzheimer’s Disease in the Ashkenazi Jewish Population”: Icahn School of Medicine at Mount Sinai, University of Washington Department of Biostatistics, and Boston University Genome Science Institute (2020–2021)
  • “APOE Modifier Analysis”: CHARGE Consortium’s neuro-CHARGE working group (2020–2021)
  • “Mapping Autoimmune Phenotypes in Multiplex Families”: Center for Genomics & Human Genetics at Feinstein Institutes for Medical Research (2018–2021)
  • “Peptides that Resemble Mammalian Melanocortin Hormones α-MSH and ACTH in Structure and Anti-Inflammatory Capabilities”: Laboratory for Diabetes and Diabetes-Related Research at Feinstein Institutes for Medical Research (2018–2020)
  • “Precision Oncology: Lessons Learned and Challenges for the Future”: Center for Genomics & Human Genetics at Feinstein Institutes for Medical Research (2019)
  • “Revealing the Landscape of Pan-cancer Predisposition across Pediatric, Adolescent, and Adult Populations”: Center for Genomics & Human Genetics at Feinstein Institutes for Medical Research (2018)

Department of Engineering at Hofstra University (Hempstead, NY) and Weill Cornell Medicine Graduate School of Medical Sciences (New York, NY)
Research Volunteer
September 2017–May 2023

• Mentors: Sina Y. Rabbany, PhD, Shahin Rafii, MD, and Brisa Palikuqi, PhD
• Responsibilities
  • Analyzed images of angiogenesis in normal colon tissue and in tissue with an upregulated transcription factor causing increased vessel growth, to justify use of this transcription factor in artificial tissue development
  • Used fractal mathematics to supplement typical vessel growth metrics, such as density
  • Used atomic force microscopy (AFM) to characterize mechanical properties of endothelial cells

Center for Genomics & Human Genetics, Feinstein Institutes for Medical Research, Northwell Health (Manhasset, NY)
Visiting Scholar
November 2016–June 2018

• Mentors: Peter K. Gregersen, MD, and Kim R. Simpfendorfer, PhD
• Responsibilities
  • Completed undergraduate honors thesis project, regarding genetic risk for rheumatoid arthritis
  • Found no association between any CNV in the human IRF1 or TNIP1 genes and rheumatoid arthritis

Center for Oncology & Cell Biology, Feinstein Institutes for Medical Research, Northwell Health (Manhasset, NY)
Visiting Scholar
October 2015–September 2016

• Mentors: Tom L. Rothstein, MD, PhD, and Tam Quach, PhD
• Responsibilities
  • Gathered and analyzed flow cytometry data for B lymphocytes, focusing on human B-1 cells
  • Prepared experiments to investigate the role of B-1 cells in autoimmune & age-related diseases

Kaplan Test Prep (New York, NY)
Instructor
November 2017–February 2020

• Instructor, tutor, and coach for MCAT, ACT, and SAT test prep courses
• Created lessons plans, assisted in curriculum development, and mentored students

Einstein Community Health Outreach (ECHO), Albert Einstein College of Medicine (Bronx, NY)
Clinic Volunteer
June 2017–September 2019

• Worked with third-year medical students and attending physicians to gather vitals and histories
• Informed uninsured patients about good practices to improve their lifestyle and health decisions and create goals

Department of Chemistry, Hofstra University (Hempstead, NY)
Teaching Assistant
September 2017–May 2018

• Assisted Prof. Nanette Wachter-Jurcsak with collaborative learning groups
• Tutored students in organic chemistry and biochemistry

Education

Delenko J, Xue X, Chatterjee PK, Hyman N, Shih AJ, Adelson RP, Safaric Tepes P, Gregersen PK, Metz CN. Quercetin enhances decidualization through AKT-ERK-p53 signaling and supports a role for senescence in endometriosis. Reprod. Biol. Endocrinol. Published August 2024,
DOI: 10.1186/s12958-024-01265-z

Adelson RP, Ciobanu M, Garikipati A, Castell NJ, Barnes G, Tawara K, Singh NP, Rumph JK, Mao Q, Vaish A, Das R. Family-centric applied behavior analysis promotes sustained treatment utilization and attainment of patient goals. Cureus. Published June 2024, DOI: 10.7759/cureus.62377

Adelson RP, Garikipati AG, Zhou Y, Ciobanu M, Tawara K, Barnes G, Singh NP, Mao QQ, Das R. Machine learning approach with harmonized multinational datasets for enhanced prediction of hypothyroidism in patients with type 2 diabetes. Diagnostics. Published May 2024, DOI: 10.3390/diagnostics14111152

Adelson RP, Ciobanu M, Garikipati A, Castell NJ, Singh NP, Barnes G, Rumph JK, Mao Q, Roane HS, Vaish A, Das R. Family-centric applied behavior analysis facilitates improved treatment utilization and outcomes. J. Clin. Med. Published April 2024, DOI: 10.3390/jcm13082409

Adelson RP, Garikipati A, Maharjan J, Ciobanu M, Barnes G, Singh NP, Dinenno FA, Mao Q, Das R. Machine learning approach for improved longitudinal prediction of progression from mild cognitive impairment to Alzheimer’s disease. Diagnostics. Published December 2023, DOI: 10.3390/diagnostics14010013

Jin H, Aziz M, Murao A, Kobritz M, Shih AJ, Adelson RP, Brenner M, Wang P. Antigen-presenting aged neutrophils induce CD4⁺ T cells to exacerbate inflammation in sepsis. Journal of Clinical Investigation. Published July 2023, DOI: 10.1172/JCI164585

Metz CN, Xue X, Chatterjee PK, Adelson RP, Brines M, Tracey KJ, Gregersen PK, Pavlov VA. Increased plasma lipopolysaccharide-binding protein and altered inflammatory mediators in overweight women suggest a state of subclinical endotoxemia. bioRxiv. Preprint published May 2023, DOI: 10.1101/2023.05.18.540879

Shih AJ, Adelson RP, Vashistha H, Khalili H, Nayyar A, Puran R, Herrera R, Chatterjee PK, Lee AT, Truskinovsky AM, Elmaliki KM, DeFranco M, Metz CN, Gregersen PK. Single cell analysis of menstrual endometrial tissue reveals phenotypes associated with endometriosis. BMC Medicine, submitted March 2022, accepted September 2022. Published September 2022, DOI: 10.1186/s12916-022-02500-3

Gómez-Salinero JM, Izzo F, Lin Y, Houghton S, Itkin T, Geng F, Bram Y, Adelson RP, Inghirami GG, Xiang JZ, Lis R, Redmond D, Schreiner R, Rabbany SY, Landay DA, Schwartz RE, Rafii S. Temporal and functional determinants of intra-hepatic vascular homeostatic specialization. Cell Stem Cell, accepted January 2022. Published April 2022, DOI: 10.1016/j.stem.2022.03.002.

Adelson RP, Palikuqi B, Weiss Z, Checco A, Schreiner R, Rafii S, Rabbany SY. Morphological characterization of Etv2 explants using fractal analysis and atomic force microscopy. Microvascular Research, submitted April 2021, accepted June 2021. Published November 2021, DOI: 10.1016/j.mvr.2021.104205.

Fulton-Howard B, Goate AM, Adelson RP, Koppel J, Gordon ML, Alzheimer’s Disease Genetics Consortium, Barzilai N, Atzmon G, Davies P, Freudenberg-Hua Y. Greater effect of polygenic risk score for Alzheimer’s disease among younger cases who are Apolipoprotein E-e4 carriers. Neurobiology of Aging, submitted April 2020, accepted September 2020. Published March 2021, DOI: 10.1016/j.neurobiolaging.2020.09.014.

Adelson RP, Renton AE, Li W, Barzilai N, Atzmon G, Goate AM, Davies P, Freudenberg-Hua Y. Empirical design of a variant quality control pipeline for whole genome sequencing data using replicate discordance. Scientific Reports, submitted May 2019, accepted October 2019. Published November 6, 2019. DOI: 10.1038/s41598-019-52614-7.

Revollo ML, Mehdi S, Lowell B, Lan X, Marck M, Adelson RP, Roth J. Peptides that resemble mammalian melanocortin hormones α-MSH and ACTH in structure and anti-inflammatory capabilities are native to multiple species of gut bacteria. American Board of Pediatrics Sub-board of Pediatric Endocrinology. June 2019.

Hsu M, Freudenberg-Hua Y, Li W, Adelson RP. How can MCI, non-MCI, and normal patients be distinguished with established cognitive tests? Summer Student Poster Session, Feinstein Institutes for Medical Research, August 2019. Poster.

Revollo ML, Mehdi S, Lowell B, Lan X, Marck M, Adelson R, Roth J. Peptides that Resemble Mammalian Melanocortin Hormones α-MSH and ACTH in Structure and Anti-Inflammatory Capabilities are Native to Multiple Species of Gut Bacteria. Pediatric Research Day, Cohen’s Children’s Medical Center, May 2019. Presentation, Poster, and Abstract.

Revollo ML, Mehdi S, Lowell B, Lan X, Marck M, Adelson R, Roth J. Peptides that Resemble Mammalian Melanocortin Hormones α-MSH and ACTH in Structure and Anti-Inflammatory Capabilities are Native to Multiple Species of Gut Bacteria. Northwell Health Annual Academic Competition, Zucker School of Medicine at Hofstra/Northwell, May 2019. Presentation, Poster, and Abstract.

Adelson R, Renton A, Shah R, Abhyankar A, Barzilai N, Atzmon G, Goate A, Davies P, Freudenberg-Hua Y. Design of a Variant Quality Control Pipeline for Whole Genome Sequencing Studies Using Replicate Discordance. Biological Data Science Conference, Cold Spring Harbor Laboratory, October 2018. Presentation, Poster, and Abstract.

Adelson R, Linehan M, Bieniewicz M, Muscarello J. Gel Therapy for Osteoarthritic Articular Cartilage Repair. Senior Design Showcase, Hofstra University, May 2018. Presentation and Poster.

Adelson R. Copy Number Variation of IRF1 and TNIP1: Association with Risk for Rheumatoid Arthritis. Hofstra University, April 2018. Honors Thesis Presentation. Awarded High Honors.

Adelson R, Linehan M, Bieniewicz M, Muscarello J. Gel Therapy for Osteoarthritic Articular Cartilage Repair. Mid-Atlantic Biomaterials Day, Johns Hopkins University, March 2018. Presentation and Poster.

Adelson R. Low-Cost Power Transformer Utilizing Demagnetization and Zero-Crossing Phase Hop. Long Island Junior Science and Humanities Symposium, Stony Brook University, February 2013. Presentation and Poster.

Adelson R. Low-Cost Power Transformer Utilizing Demagnetization and Zero-Crossing Phase Hop. Long Island Science and Engineering Fair, 2013. Poster.

Adelson R, Adelson S. Fitts’s Law: Application as a Diagnostic Tool for Fine Motor Disorders. New York State Science and Engineering Fair, 2012. Poster.

Adelson R, Adelson S. Fitts’s Law: Application as a Diagnostic Tool for Fine Motor Disorders. Long Island Science and Engineering Fair, January 2012. Poster.

Adelson R. Fitts’s Law and Control Theory in the Diagnosis of Fine Motor Disorders. Al Kalfus Long Island Math Fair, 2012. Presentation and Poster.